Candida auris is a yeast fungus that was first detected in the external auditory canal of a 70-year-old female patient in Japan in 2009. Hence its name: Auris is the Latin word for ear. The fungus can cause severe diseases in humans.

Since its first appearance, this yeast fungus has already infected hundreds of people worldwide, primarily in hospitals.

Human

Candida auris is passed from person to person and via contaminated surfaces. Transmission most likely occurs as a smear infection.

Infections of the urinary tract, wounds and blood poisoning. Between 30 and 60 percent of all infections in which Candida auris enters the body are fatal.

Unlike the classic Candida yeasts, Candida auris is resistant to many conventional antifungal drugs. There are only a few antimycotics (drugs against fungal infections) available with which affected patients can be treated.

In the case of Candida auris, colonization of healthy individuals primarily has no further effects. In the case of pre-existing conditions, however, Candida auris can lead to diseases.

Candida auris was detected by us for the first time in Austria in January 2018.

Candida auris is a yeast fungus that was first detected in the external auditory canal of a 70-year-old female patient in Japan in 2009. Hence its name: Auris is the Latin word for ear. Since its first appearance, this yeast has already infected hundreds of people worldwide, primarily in hospitals. Infections of the urinary tract, wounds and blood poisoning have occurred. Unlike the classic Candida yeasts, Candida auris is resistant to many conventional antifungal agents. This is rather unusual for fungi and makes the pathogen difficult to treat. There are only a few antifungal drugs available that can be used to treat affected patients.

In January 2018, this pathogen was detected for the first time in Austria by AGES. A patient in Styria had consulted a general practitioner due to prolonged inflammation of the ear canal, who sent an ear swab to AGES for examination for microbial pathogens. The Austrian patient was successfully treated. The first Austrian description was published in the American journal Emerging Infectious Diseases.

According to the European Centre for Disease Prevention and Control (ECDC), a total of 4,0112 cases were reported in Europe between 2013 and 2023 (Spain, United Kingdom, Germany, France, Belgium, Norway, Austria).

In April 2018, the ECDC identified the occurrence of Candida auris as a Europe-wide risk for hospital patients. This is due to the tendency of this new pathogen to cause outbreaks in hospitals, its resistance to conventional antifungal agents and laboratory diagnostic problems (correct pathogen detection using conventional methods [biochemical methods] is not always possible). The largest nosocomial outbreak (= transmission in hospital) to date occurred in 2015/2016 in a cardiac surgery department in London.

The US Centers for Disease Control and Prevention (CDC) estimates that between 30 and 60 per cent of all infections in which Candida auris enters the body are fatal. The agency first warned of a serious global threat in August 2017. The CDC also cites the multi-resistance of the new pathogen, the problem of correctly identifying the fungus in the laboratory using conventional detection methods, which in turn can delay the correct diagnosis and therefore the correct treatment, and the tendency of Candida auris to cause hospital outbreaks.

Other yeasts that colonise humans, such as Candida albicans, are often found on the skin and mucous membranes. They do not cause problems there. Only when the immune system is weakened for some reason do they sometimes multiply to such an extent that they can cause symptoms of illness - for example candidiasis, also known as thrush. Even in the case of Candida auris, colonisation of a healthy person primarily has no further effects. However, if there are pre-existing conditions, Candida auris can lead to symptoms such as blood poisoning, urinary tract infections or wound infections. While the classic Candida albicans diseases are all endogenous infections (the pathogen originates from the body's own flora), Candida auris is passed from person to person and via contaminated surfaces, which explains the hospital outbreaks described. Transmission most likely occurs as a smear infection. An airborne infection, as is often the case with cold viruses, can be ruled out according to current knowledge.