Mccp, formerly known as Mycoplasma sp. type F-38, belongs to the mycoplasmas, a group of cell-wallowing bacteria of the class "Mollicutes". Mccp is closely related to M. capricolum subsp. capricolum as well as to other members of the Mycoplasma mycoides cluster(Mycoplasma mycoides subsp. capri, Mycoplasma leachii, etc.).
The pathogen is difficult to isolate and requires a complex culture medium.
The disease can be peracute, acute or chronic. Acute cases occur mainly in areas where CCPP first appears. Chronic cases are more common in enzootic areas.
- Peracute: The goats show hardly any clinical symptoms and die within one to three days.
- Acute: goats show high fever (41-43°C), lethargy and anorexia followed by cough and dyspnoea.
- Chronic: Goats show chronic cough, nasal discharge and are debilitated.
All goats are susceptible, regardless of age or sex.
Pathomorphologically, the disease is characterized by a usually unilateral fibrinous pleuropneumonia with straw-colored, serofibrinous pleural effusion. The cut surface of the lung is granular to nodular (pea-sized nodules) with discharge of fibrin-rich exudate. In addition, liver-like hardened or discolored areas (hepatization) and focal necrosis may form. In the chronic form, encapsulation of the inflammatory foci and adhesions between the lung and chest wall may occur.In contrast to Mccp, where lesions are confined exclusively to the thoracic cavity, other pathogens of the Mycoplasma mycoides cluster also cause lesions in other organs and body regions.
CCPP is highly contagious and can reach a morbidity rate of up to 100%. The mortality rate is also high and can reach up to 80 %.