Contagious caprine pleuropneumonia

Mycoplasma capricolum subsp. capripneumoniae

Changed on: 02.08.2021

Animal disease categories: A D E


Contagious caprine pleuropneumonia is a highly contagious, bacterial infectious disease in goats. Transmission to humans is not possible.


Contagious caprine pleuropneumonia occurs in Africa, Asia and the Middle East. The exact distribution is not well known.

Host animals

Contagious caprine pleuropneumonia primarily affects goats. Sheep may (rarely) become ill if they are in a herd with goats. Occurrence in various wild ruminant species has been reported (wild goat, ibex, mouflon, gazelles).

Mode of transmission

Aerogenic (droplet infection)

Incubation period

6 to 10 days


Shortness of breath, cough, nasal discharge, loss of appetite and fever.


Some antibiotics (e.g. tylosin, tetracycline) have proved effective, provided they are used early.


Measures of prevention are adherence to quarantine measures and control of livestock traffic. Vaccination is possible.

Situation in Austria

Contagious caprine pleuropneumonia does not currently occur in Austria.

Professional information

Mccp, formerly known as Mycoplasma sp. type F-38, belongs to the mycoplasmas, a group of cell-wallowing bacteria of the class "Mollicutes". Mccp is closely related to M. capricolum subsp. capricolum as well as to other members of the Mycoplasma mycoides cluster(Mycoplasma mycoides subsp. capri, Mycoplasma leachii, etc.).

The pathogen is difficult to isolate and requires a complex culture medium.


The disease can be peracute, acute or chronic. Acute cases occur mainly in areas where CCPP first appears. Chronic cases are more common in enzootic areas.

  • Peracute: The goats show hardly any clinical symptoms and die within one to three days.
  • Acute: goats show high fever (41-43°C), lethargy and anorexia followed by cough and dyspnoea.
  • Chronic: Goats show chronic cough, nasal discharge and are debilitated.

All goats are susceptible, regardless of age or sex.

Pathomorphologically, the disease is characterized by a usually unilateral fibrinous pleuropneumonia with straw-colored, serofibrinous pleural effusion. The cut surface of the lung is granular to nodular (pea-sized nodules) with discharge of fibrin-rich exudate. In addition, liver-like hardened or discolored areas (hepatization) and focal necrosis may form. In the chronic form, encapsulation of the inflammatory foci and adhesions between the lung and chest wall may occur.In contrast to Mccp, where lesions are confined exclusively to the thoracic cavity, other pathogens of the Mycoplasma mycoides cluster also cause lesions in other organs and body regions.

CCPP is highly contagious and can reach a morbidity rate of up to 100%. The mortality rate is also high and can reach up to 80 %.


Differential diagnosis

  • Peste des petits ruminants (PPR)
  • Pasteurellosis
  • Infectious agalactia of sheep and goats

The pathogen is unequivocally detected by PCR or by cultural cultivation from tissue. As cultural detection is very demanding, PCR is the method of choice.

Serological tests (complement fixation reaction, latex agglutination test, cELISA) are possible on a herd basis.

Examination material in vivo: bronchoalveolar lavage, pleural exudate (by puncture), serum (in pairs at intervals of 3-8 weeks)Examination matioal post mortem:lung lesions (transition healthy to diseased area), pleural exudate, mediastinal lymph nodesTissue should be transported refrigerated or at -20 °C.

Contact, Forms

Institute for Veterinary Medicine MödlingRobertKoch-Gasse 172340 MödlingTel: +43 50 555-38112Fax: +43 50 555-38529E-Mail: vetmedno.Spam.moedlingno@Spam@ages

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