The most important measure in Cholera therapy is the timely and sufficient balance of the body’s electrolyte and water levels. This can be achieved orally, if possible, with 20g glucose + 1.5g KCl + 2.5g NaCl + 3.5g Na-bicarbonate. In severe cases, IV drips must be used. Administering antibiotics to patients plays a minor role. They reduce the duration and intensity of diarrhoea in severe cases. Erythromycine, Tetracycline, Doxycycline and Ciprofloxacine are recommended antibiotics.
A therapy using antibiotics should be definitely considered for extraintestinal Vibrio infections.
Hands must be cleaned thoroughly (washing hands with soap is sufficient!) after each visit to the toilet and before handling food (including drinking water). Moreover, all items and surfaces that have likely come/have visibly come into contact with the patient’s excrement should be disinfected.
An inactive, oral vaccine has been available in Austria since 2003. An oral vaccine administered twice (at an interval from 1-6 weeks) protects for about six months up to a maximum of two years. The protection level is 90%.
Patients who have suffered an infection can only expect incomplete immunity afterwards.